CDX Orthotopic Tumor Model

Classification:

Oncology


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Product Description

The orthotopic xenograft model is a system in which tumor cells are implanted at the site of the organ of origin. This organ-specific site presumably provides the tumor cells with an optimal environment for growth and progression. For this reason, there has been a recent shift in cancer drug discovery to using orthotopic tumors to better model human cancers in animals. Because of its clinical-like patterns and high incidence of metastasis, this model has been used extensively as an in vivo evaluation model for anticancer drugs.  The application of some state of the art imaging technologies allow for the non-invasive, real-time measurements of orthotopic tumors and metastases.

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